| Laura and John Arnold Foundation | Houston | 6794 | $2.1B | $308K |
| Michael & Susan Dell Foundation | Austin | 8703 | $1.5B | $173K |
| Musk Foundation | Austin | 254 | $1.4B | $5.7M |
| Je and Le Mabee Foundation Inc | Midland | 1349 | $1.0B | $767K |
| Houston Endowment Inc | Houston | 4665 | $981.5M | $210K |
| The Moody Foundation | Galveston | 2713 | $869.8M | $321K |
| The Brown Foundation Inc | Houston | 6300 | $818.7M | $130K |
| The Rees-Jones Foundation | Dallas | 1718 | $546.8M | $318K |
| Kinder Foundation | Houston | 764 | $533.7M | $699K |
| Bhp Foundation | Houston | 353 | $470.3M | $1.3M |
| The Robert a Welch Foundation | Houston | 688 | $392.2M | $570K |
| Rainwater Charitable Foundation | Fort Worth | 2775 | $389.9M | $141K |
| Ting Tsung & Wei Fong Chao Foundation | Houston | 1952 | $336.8M | $173K |
| Dan L Duncan Foundation | Houston | 490 | $304.5M | $621K |
| The T Boone Pickens Foundation | Dallas | 18 | $268.6M | $14.9M |
| Texas Instruments Foundation | Dallas | 37658 | $239.9M | $6K |
| Scharbauer Foundation Inc | Midland | 747 | $220.5M | $295K |
| Meadows Foundation Inc | Dallas | 1456 | $218.2M | $150K |
| Impetus Foundation | San Antonio | 425 | $216.0M | $508K |
| Burnett Foundation | Fort Worth | 74 | $214.2M | $2.9M |
| Knobloch Family Foundation | Houston | 397 | $184.9M | $466K |
| The Powell Foundation | Houston | 2146 | $183.8M | $86K |
| Dian Graves Owen Foundation | Abilene | 1590 | $181.3M | $114K |
| F M H Foundation | Midland | 694 | $171.5M | $247K |
| Stanley E Fulton Family Foundation | Dallas | 222 | $169.9M | $765K |
| The Cullen Foundation | Houston | 248 | $164.6M | $664K |
| Hildebrand Foundation | Houston | 1095 | $158.3M | $145K |
| The Mulva Family Foundation | Austin | 208 | $156.2M | $751K |
| Ainslie Foundation | Dallas | 916 | $148.2M | $162K |
| Heavenly Fathers Foundation | Cisco | 15 | $139.1M | $9.3M |
| The Wildcat Foundation | Fort Worth | 332 | $137.7M | $415K |
| The Karakin Foundation | Abilene | 1021 | $133.6M | $131K |
| The Jay Pritzker Foundation | Houston | 251 | $133.1M | $530K |
| Centerpoint Energy Foundation Inc | Houston | 3189 | $132.7M | $42K |
| Albert & Margaret Alkek Foundation | Houston | 452 | $115.0M | $254K |
| Eula Mae and John Baugh Foundation | Jersey Village | 319 | $109.5M | $343K |
| The Lanier Theological Library Foundation | Houston | 180 | $103.1M | $573K |
| Santander Consumer Usa Inc Foundation | Dallas | 465 | $98.6M | $212K |
| Kickapoo Springs Foundation | Abilene | 1082 | $97.7M | $90K |
| Simon Bolivar Foundation Inc | Houston | 396 | $97.7M | $247K |
| The Legett Foundation | Abilene | 1249 | $97.5M | $78K |
| Stoller Foundation | Houston | 1100 | $96.2M | $87K |
| The Ewing Halsell Foundation | San Antonio | 516 | $92.9M | $180K |
| The Lester and Sue Smith Foundation | Houston | 62 | $90.8M | $1.5M |
| Crow Family Foundation Inc | Dallas | 2 | $90.1M | $45.0M |
| The Sarah and Ross Perot Jr Foundation | Dallas | 479 | $90.0M | $188K |
| The Addy Foundation | Dallas | 551 | $87.8M | $159K |
| Bnsf Railway Foundation | Fort Worth | 15121 | $87.0M | $6K |
| Hamon Charitable Foundation | Dallas | 341 | $85.8M | $251K |
| The Klesse Foundation | San Antonio | 13 | $85.3M | $6.6M |
| The Usaa Foundation Inc | San Antonio | 9 | $84.1M | $9.3M |
| The Sheth Sangreal Foundation | Austin | 118 | $83.4M | $707K |
| Once Upon a Time Foundation | Fort Worth | 3448 | $79.3M | $23K |
| The Charles Butt Foundation | San Antonio | 709 | $76.3M | $108K |
| The Pogue Foundation | Dallas | 14 | $75.2M | $5.4M |
| Kate Marmion Charitable Foundation | San Antonio | 154 | $75.1M | $488K |
| Beloved in Christ Foundation | Austin | 115 | $75.1M | $653K |
| The Thirteen Foundation | Cisco | 11 | $74.5M | $6.8M |
| Boone Family Foundation | Dallas | 711 | $74.3M | $104K |
| Nancy Smith Hurd Foundation | San Antonio | 748 | $72.7M | $97K |
| The Greehey Family Foundation | San Antonio | 9 | $72.4M | $8.0M |
| Norman H Read 1985 Trust | Amarillo | 49 | $71.8M | $1.5M |
| Tres Grace Family Foundation | San Antonio | 212 | $70.2M | $331K |
| Heb Tournament of Champions Charitable Trust | San Antonio | 11 | $66.9M | $6.1M |
| Harvey E Najim Charitable | San Antonio | 1439 | $65.7M | $46K |
| The David B Miller Family Foundation | Dallas | 116 | $65.1M | $561K |
| Srb Charitable Corporation | Fort Worth | 81 | $63.6M | $785K |
| Gene & Jerry Jones Family | Frisco | 161 | $63.6M | $395K |
| Eleanor Crook Foundation | San Marcos | 395 | $62.7M | $159K |
| East Texas Medical Center Foundation | Tyler | 80 | $62.6M | $782K |
| The Nau Foundation | Houston | 49 | $60.6M | $1.2M |
| Selma E Andrews Trust | Dallas | 72 | $60.4M | $839K |
| The Philecology Foundation | Fort Worth | 46 | $58.8M | $1.3M |
| Thomas M Helen Mckee & | Fort Worth | 1324 | $58.0M | $44K |
| The Whalley Foundation | Houston | 917 | $56.9M | $62K |
| Prentice Farrar Brown and Alline Ford Brown | Dallas | 199 | $55.8M | $281K |
| The Carl a Davis and Lois E Davis | Houston | 326 | $55.5M | $170K |
| Lewis Humphreys Charitable Trust | Dallas | 383 | $55.4M | $145K |
| Hirsch Family Foundation | Dallas | 556 | $55.3M | $99K |
| The Rory and Howard Meyers Family | Dallas | 16 | $55.0M | $3.4M |
| The Alcon Foundation Inc | Fort Worth | 1107 | $54.9M | $50K |
| Mark Cuban Foundation | Dallas | 384 | $54.3M | $141K |
| Md Anderson Foundation | Houston | 526 | $54.2M | $103K |
| Samuels Family Foundation | Bellaire | 115 | $53.9M | $468K |
| William a Brookshire Foundation | Plano | 47 | $52.9M | $1.1M |
| Louis L Borick Foundation | Houston | 1364 | $52.2M | $38K |
| Infosys Foundation Usa | Richardson | 654 | $50.4M | $77K |
| Ed Foundation | Austin | 224 | $50.3M | $225K |
| Pema Foundation | Houston | 62 | $50.1M | $807K |
| Melza M and Frank Theodore Barr | Houston | 138 | $49.7M | $360K |
| The Woodforest Charitable Foundation | The Woodlands | 2729 | $49.5M | $18K |
| Hector and Gloria Lopez Foundation | Austin | 42 | $48.6M | $1.2M |
| Garry Weber Foundation | Dallas | 29 | $48.5M | $1.7M |
| James N Mccoy Foundation | Wichita Falls | 718 | $48.0M | $67K |
| Endowment for Regional Sustainability | The Woodlands | 16 | $47.5M | $3.0M |
| The Constantin Foundation Inc | Dallas | 254 | $47.4M | $187K |
| Jiv Daya Foundation | Plano | 12 | $46.1M | $3.8M |
| Jlh Foundation | Katy | 84 | $45.3M | $539K |
| The Ware Foundation | Amarillo | 11 | $43.6M | $4.0M |
| The Deason Foundation | Dallas | 200 | $43.6M | $218K |
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